Born in Moschato, suburb of Athens, Vardis met several legendary Greek musicians when he was six years old, including Vassilis Tsitsanis. Vardis established a 40-year career as a composer and singer, collaborating with well-known Greek singers: George Dalaras, Yiannis Parios, Vasilis Papakonstantinou, Haris Alexiou, Dimitra Galani, Anna Vissi.
During the 90's and 00's he worked as a composer with popular singers such as Keti Garbi, Yannis Vardis, Antonis Remos, Pegy Zina, Stelios Rokos, Natassa Theodoridou, Giannis Ploutarhos and more.
In 1981, Vardis was diagnosed with cancer. In 2013, he was transferred to Hanover, Germany, to undergo surgery described as successful. However, he died on 2 September 2014 at Hygeia Hospital in Athens at the age of 66.